nuclear lamina protein (核纤层蛋白) -题库考试答案搜索网

nuclear lamina protein (核纤层蛋白)

名词解释题

2022-03-25 19:08

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脊椎动物细胞中有三种类型的核纤层蛋白（A，B，C），核纤层蛋白A和C是由同一个转录单位编码的，只不过是通过可变剪接形成不同的mRNA。它们在肽链上的差别是：核纤层蛋白A的C末端比核纤层蛋白C的C末端多133个氨基酸残基。核纤层蛋白B是由另一个转录单位编码的，通过转录后的修饰，在羧基端添加了疏水的异丙基，添加的脂肪酸帮助核纤层蛋白B插入到核膜的内脂层。三种类型的核纤层蛋白都以二聚体的形式存在，有球形的头和尾部结构域以及一个杆状的α螺旋中心。这些核纤层蛋白二聚体以头-头、尾-尾相接的方式形成核纤层。

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标签：细胞增殖及其调控大学试题理学

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