治疗慢性心功能不全和逆转心肌肥厚并能降低病死率的药物是（）。 -题库考试答案搜索网

治疗慢性心功能不全和逆转心肌肥厚并能降低病死率的药物是（）。

单选题

2021-12-25 13:05

A、强心苷
B、哌唑嗪
C、硝酸甘油
D、酚妥拉明
E、卡托普利

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试题解析

ACEI类药物不仅可以抑制循环RAS，达到扩张血管，抑制交感神经兴奋性从而改善心功能不全时血流动力学障碍，减轻淤血状态，改善左室功能。而且可以抑制心脏组织中的RAS，限制和延缓心肌重塑，逆转左室肥厚，从而达到维护心肌功能，推迟心衰进展，明显改善心力衰竭患者的预后，降低病死率。卡托普利为最早用于临床的ACEI。ACEI不宜用于伴严重肾衰竭、双侧肾动脉狭窄和低血压的病人，妊娠哺乳期妇女禁用。血管扩张剂酚妥拉明、硝酸甘油均可用于治疗慢性心功能不全，对改善血流动力学有良好效应。强心苷与哌唑嗪均可用于治疗慢性心功能不全

标签：心脏内科北京住院医师神经内科Ⅰ阶段基础综合第六章药理学专业综合第十二章内科主要疾病全科医学住院医师

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