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首关消除(first-pass effect)

名词解释题
2022-02-26 20:38
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又称首过效应、首过消除、第一关卡效应,口服药物从胃肠道吸收入门静脉系统的药物在到达全身血循环前必先通过肝脏,如果肝脏对其代谢能力很强或由胆汁排泄的量很大,则使进入全身血循环内的有效药量明显减少,这种作用称为首关消除。


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翻译:With Average or With Particular Average(WA or WPA)()
首关消除(first-pass effect)
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