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患者,女,77岁。入院诊断为:冠心病,肺部感染,2型糖尿病。入院后,继续口服格列本K (优降糖)5mg,每日一次,以及抗感染治疗 等。复查空腹血糖7.1mmol/L。患者主诉腰痛剧,X线摄片提示:第3腰椎压缩性改变,遂予布洛芬(芬必得)0.3g,每日2次,口服,腰痛逐渐缓解。至第8天下午,患者突然神志昏迷,测血糖仅为0.4mmol/L,考虑为低血糖性昏迷。经予50%葡萄糖注射液60ml,静脉注射,神志逐渐 转清,唯停药布洛芬(芬必得),后患者未再昏迷。经多次复查血糖均在7.0mmol/L左右


问题2:此患者低血糖昏迷的原因是

单选题
2021-07-17 21:41
A、患者患多种疾病”体弱,易致低血糖
B、老年人代谢能力低下,正常成人剂量的优降糖作用加强 
C、布洛芬(芬必得)有酶抑作用,可抑制代谢格列本脲(优降糖)的肝药酶,使i后者血药浓度增加,降血糖作用增加而致低血糖 
D、布洛芬(芬必得)可置换格列本服(优降糖)与血浆蛋白的结合位点,使游离格列本脲(优降糖)血浓增加,降血糖作用增加而致低血糖 
E、芬必得系布洛芬的缓释制剂,属非甾体抗炎镇痛药,老年人忌用非甾体制剂
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正确答案
D

试题解析

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