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nuclear localization signal, NLS (核定位信号)

名词解释题
2022-03-25 19:08
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是另一种形式的信号肽，可位于多肽序列的任何部分。一般含有4～8个氨基酸，且没有专一性，作用是帮助亲核蛋白进入细胞核。入核信号与导肽的区别在于：
①由含水的核孔通道来鉴别；
②入核信号是蛋白质的永久性部分，在引导入核过程中，并不被切除，可以反复使用，有利于细胞分裂后核蛋白重新入核。有多种类型的核定位信号，这些信号都具有一个带正电荷的肽核心。

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标签： 细胞核与染色体 大学试题 理学
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