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试述动作电位产生的机制。

问答题
2022-04-02 14:56
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正确答案
动作电位的产生机制:细胞受刺激→膜上少量电压门控Na+通道开放(激活)→Na+顺电-化学梯度→少量Na+内流→膜去极化到某一电位水平(阈电位)→大量Na+通道开放→大量Na+内流→形成AP上升支(去极相)→达到Na+平衡电位,膜电位内正外负(动力:电位差和浓度差;阻力:电位差)→Na+通道失活→膜上K+通道开放→膜内K+顺电-化学梯度向外扩散→膜内电位变负→AP下降支(复极相)→K+平衡电位→Na+通道恢复(复活)。恢复到静息电位前的后电位还有钠泵的参与。

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