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锚定连接(anchoring junction)

名词解释题
2023-02-02 17:35
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通过跨膜蛋白进行细胞的锚定,将细胞与细胞、细胞与细胞外基质同细胞骨架连接起来的细胞连接方式称为锚定连接。也有人将这种连接称为斑块连接(plaque-bearing  junction),因为这种连接主要是通过细胞质膜内侧的斑块(plaque)进行连接的。
锚定连接是动物各组织中广泛存在的一种细胞连接方式,通过粘着蛋白、整联蛋白和细胞骨架体系以及细胞外基质的相互作用,将相邻两细胞连接在一起。根据跨膜蛋白是同肌动蛋白纤维相连还是同中间纤维相连,将斑块连接分为粘着连接(粘着带、粘着斑)和桥粒(桥粒和半桥粒)两大类。


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