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简述HIV的传播途径和致病机理。

问答题
2021-07-18 13:10
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正确答案
性传播、血液传播、垂直传播;机制:HIV的增殖导致CD4+T细胞融合,形成多核巨细胞,导致细胞死亡;导致特异性CTL细胞对CD4+细胞特异性杀伤,特异性抗体通过ADCC作用破坏CD4+细胞;病毒感染诱导CD4+T细胞凋亡。

试题解析
性传播、血液传播、垂直传播;机制:HIV的增殖导致CD4+T细胞融合,形成多核巨细胞,导致细胞死亡;导致特异性CTL细胞对CD4+细胞特异性杀伤,特异性抗体通过ADCC作用破坏CD4+细胞;病毒感染诱导CD4+T细胞凋亡。

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