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关于LAK细胞,下列说法不对的是()。

单选题
2021-12-28 10:38
A、具有细胞毒性效应
B、能被大剂量IL-2诱导
C、其实质是NK细胞
D、较NK细胞具有更广谱的杀瘤作用
E、其抗肿瘤的生物应答机制目前尚不十分清楚
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正确答案
C

试题解析
LAK是淋巴因子激活的杀伤细胞,实质为大剂量IL-2诱导的体外刺激人体外周血单个核细胞(包括NK细胞和T细胞),经培养扩增而得到,具有细胞毒性效应。虽有部分细胞为NK细胞诱导而得,但LAK非NK细胞,且较NK细胞具有更广谱的杀瘤作用,其抗肿瘤的生物应答机制目前尚不十分清楚。

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