女性,17岁。心慌多汗半年。近1个月出现多饮、多尿就诊。体检:明显消瘦,双眼略突出,甲状腺Ⅱ度大,双上极可闻及血管杂音。血Fr333.5pmol/L,FT440pmol/L,TSH0.01mU/L(0.01μU/ml)在治疗患者甲状腺功能亢进时加用了普萘洛尔,在治疗过程中下列哪种情况的变化是至关重要的()
A campus emergency ______ occur at any time of the day or night, weekend, or holiday, with little or no warning.
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