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治疗慢性心功能不全和逆转心肌肥厚并能降低病死率的药物是（）

单选题
2021-12-25 23:51
A、强心苷
B、哌唑嗪
C、硝酸甘油
D、酚妥拉明
E、卡托普利
查看答案
正确答案
E
试题解析
ACEI类药物不仅可以抑制循环RAS，达到扩张血管，抑制交感神经兴奋性从而改善心功能不全时血流动力学障碍，减轻淤血状态，改善左室功能。而且可以抑制心脏组织中的RAS，限制和延缓心肌重塑，逆转左室肥厚，从而达到维护心肌功能，推迟心衰进展，明显改善心力衰竭患者的预后，降低病死率。卡托普利为最早用于临床的ACEI。ACEI不宜用于伴严重肾衰竭、双侧肾动脉狭窄和低血压的病人，妊娠哺乳期妇女禁用。血管扩张剂酚妥拉明、硝酸甘油均可用于治疗慢性心功能不全，对改善血流动力学有良好效应。强心苷与哌唑嗪均可用于治疗慢性心功能不全
标签： 综合ICU 北京住院医师急诊科Ⅰ阶段 心血管内科 上海住院医师康复医学科 急诊科住院医师
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